STUDYING THE KEY ROLE OF INFLAMMATION IN DISEASE PROGRESSION AND SEVERITY


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  • Up-regulation and suppression of Type I and Type II interferons (IFNα, IFNγ) as early predictors of disease severity
  • Pro-inflammatory cytokines (GM-CSF, IL-2, IL-6, IL-10, IL-12p70, TNFα) for early detection of imbalanced Th1 and Th2 response and risk for severe cytokine release
  • Biomarkers of chronic airway inflammatory disease (IL-4, IL-5, IL-13)
  • Airway remodeling (MMP-9) in virus-induced chronic pulmonary disease