Discovery Fueled by Ultrasensitivity

Get Ultrasensitive Biomarker Measurements with Simoa® Bead Technology

From discovery to diagnostics, Quanterix’s ultrasensitive biomarker detection technology is fueling breakthroughs made possible through its unparalleled sensitivity and flexibility. Simoa® technology has delivered the gold standard for earlier biomarker detection in blood, serum, or plasma, with the ability to quantify proteins that are far lower than the Level of Quantification (LoQ). Our industry-leading precision instruments, digital immunoassay technology, and CLIA-certified Accelerator laboratory support research that advances disease understanding and management in neurology, oncology, immunology, cardiology, and infectious disease.  

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Simoa® Bead Technology

Ultrasensitive Biomarker Detection

Our Simoa® Bead Technology allows researchers to measure biomarkers at femtogram levels with simple and scalable workflows.

How it works:  

  1. Paramagnetic particles coupled with antibodies that bind to specific targets are added to the sample. 
  2. Detection antibodies capable of generating fluorescent product are added, resulting in an immunocomplex consisting of the bead-bound protein, and detection antibody. 
  3. The sample is loaded into arrays in the Simoa® disc where each microwell is sized to admit one bead and the presence of a bound protein is indicated by a fluorescent signal from the bead. Results are digital- meaning each bead either contains an analyte, along with detection antibody, or it does not. 
  4. Results can be viewed and analyzed on the board or exported for further analysis to commonly used software packages or LIMS systems. 

Quanterix offers two instruments that utilize bead technology. The HD-X™ Automated Immunoassay Analyzer offers a fully automated Simoa® bead-based immunoassay platform designed to multiplex up to 4 biomarkers in a single assay with unrivaled sensitivity. The SR-X™ Biomarker Detection System is our semi-automated benchtop instrument for running bead-based assays.   

Complete the form to the left to learn more about our Simoa® bead technology systems. 

Our Current Portfolio

Choose The Right Platform For Your Research.

Simoa® Accelerator Laboratory 

Utilize our CLIA-certified laboratory as a cost-effective, outsourced solution for your custom biomarker and biopharmaceutical research, assay development, and clinical sample testing needs.

HD-X™ Automated Immunoassay Analyzer

The HD-XTM Automated Immunoassay Analyzer is the latest model of the fully automated Simoa bead-based immunoassay platform. The HD-X delivers increased productivity, user flexibility, unparalleled sensitivity and best in class assay performance. 

Simoa® Homebrew Assays

Quanterix offers the flexibility of multiplex homebrew assay development to minimize required sample volume; providing full kits that include all reagents and training required to develop these custom homebrew assays.